What is the mechanism of action of Vigora 100 Mg?

[joniscosttale]

Vigora 100 mg contains sildenafil citrate, which is a medication primarily used to treat erectile dysfunction (ED) in men. Sildenafil citrate works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), leading to increased blood flow to the penis during sexual stimulation. Here's a breakdown of the mechanism of action of Vigora 100 mg: Nitric Oxide Release: When a man is sexually stimulated, nitric oxide (NO) is released in the erectile tissue of the penis. Nitric oxide activates an enzyme called guanylate cyclase, which leads to increased levels of cyclic guanosine monophosphate (cGMP). Smooth Muscle Relaxation: Elevated levels of cGMP cause the smooth muscles in the erectile tissue of the penis to relax, allowing blood to flow into the corpora cavernosa (the erectile chambers of the penis). Vigora 100 Mgrelaxation of smooth muscle and increased blood flow result in an erection. PDE5 Inhibition: Normally, cGMP is broken down by the enzyme phosphodiesterase type 5 (PDE5), which limits the duration of the erection. Sildenafil citrate, the active ingredient in Vigora 100 mg, selectively inhibits PDE5, preventing the breakdown of cGMP and prolonging its effects. Prolonged Erection: By inhibiting PDE5, sildenafil citrate allows cGMP levels to remain elevated, leading to sustained relaxation of smooth muscle and prolonged blood flow into the penis. This results in a firmer and longer-lasting erection, improving erectile function in men with ED. It's important to note that sexual stimulation is still required for sildenafil citrate to produce an erection. Vigora 100 mg does not automatically induce an erection; rather, it enhances the body's natural response to sexual stimulation. Additionally, sildenafil citrate is not a cure for erectile dysfunction but rather a treatment that helps manage the symptoms of ED when taken as prescribed.